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In vitro selection and analysis of SARS-CoV-2 nirmatrelvir resistance mutations contributing to clinical virus resistance surveillance

2024; American Association for the Advancement of Science; Volume: 10; Issue: 30 Linguagem: Inglês

10.1126/sciadv.adl4013

2375-2548

Yuao Zhu, Irina Yurgelonis, Stephen Noell, Qingyi Yang, Shunjie Guan, Zheng-Hui Li, Li Hao, Hussin A. Rothan, K. Devendra, Patricia McMonagle, Mary Lynn Baniecki, S.E. Greasley, Olga Plotnikova, Jonathan Lee, Jennifer Nicki, Rose Ann Ferre, Laura J. Byrnes, Wei Liu, Timothy K. Craig, Claire M. Steppan, Paul Liberator, Holly Soares, Charlotte Allerton, Annaliesa S. Anderson, Rhonda D. Cardin,

Animal Virus Infections Studies

To facilitate the detection and management of potential clinical antiviral resistance, in vitro selection of drug-resistant severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) against the virus M