Impact of Chemotherapy and Radiation on Skin Health in Cancer Patients
2024; Volume: 4; Issue: 76 Linguagem: Inglês
10.22533/at.ed.1594762413081
ISSN2764-0159
AutoresThaís Pedra Oliveira, Marina Diniz Dias, Camila Bidoia Berlanga, Osmar da Cruz Catharin, Marcos Aurélio dos Santos Roman, Maria Cecília Merege, Elizabeth C S R Senra, Luis Felipe Villela Westin, Oiarbides Melo de Lima, Paula Regina de Oliveira Santos, Maria Lúcia Brito de Araujo Paysano, Ana Paula Bonafin, Mauricio Lopes da Silva Netto,
Tópico(s)Cancer Treatment and Pharmacology
ResumoINTRODUCTION Solid organ cancers such as lung, breast, prostate, and colorectal cancers are prevalent malignancies worldwide, with significant morbidity and mortality.The treatments for these cancers, including surgery, chemotherapy, radiation therapy, and targeted therapies, have advanced considerably.However, these treatments often lead to various dermatological side effects that can profoundly impact patients' quality of life.Early detection and management of these side effects are crucial for maintaining patient wellbeing.Dermatologists play a vital role in this multidisciplinary care approach, diagnosing and treating skin-related toxicities caused by cancer therapies.OBJETIVE To provide a comprehensive overview of the dermatological side effects associated with solid organ cancer treatments.METHODS This is a narrative review which included studies in the MEDLINE -PubMed (National Library of Medicine, National Institutes of Health), COCHRANE, EMBASE and Google Scholar databases, using as descriptors: "Oncologic Dermatology" AND "Chemotherapy Side Effects" OR "Radiation Dermatitis" OR "Targeted Therapy Skin Toxicities" OR "Patient-Centered Dermatologic Care"in the last years. RESULTS AND DISCUSSIONThe incidence of dermatological side effects in cancer patients is significant, with varying prevalence rates depending on the therapy type.Chemotherapyinduced rashes, radiation dermatitis, and hand-foot syndrome are common, affecting patients' daily activities and quality of life.The severity of these side effects ranges from mild erythema to life-threatening conditions like Stevens-Johnson syndrome.Effective management strategies include pharmacological interventions such as corticosteroids and antibiotics, along with preventive measures like patient education and skincare regimens.The psychosocial impact of these side effects is profound, necessitating comprehensive
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