Artigo Acesso aberto Revisado por pares

Colorimetric Hybridization Sensor for DNA Mimic of a SARS-CoV-2 RNA Marker: Direct and Inverse Bioanalysis

2024; American Chemical Society; Volume: 4; Issue: 6 Linguagem: Inglês

10.1021/acsmeasuresciau.4c00043

ISSN

2694-250X

Autores

Zia Syed, Sathya Samaraweera, Zhuo Wang, James Kelby Schrader, Colton Scott, Joshua Schut, Dozier Johnson Smith, Joshua D. Ramsey, Sadagopan Krishnan,

Tópico(s)

SARS-CoV-2 detection and testing

Resumo

This article presents a colorimetric visual biosensor designed for direct application in undiluted biofluids, which holds significant promise for point-of-need applications. Unlike traditional biosensors that struggle with heavily diluted sample matrices, the presented biosensor does not require any instrumentation or trained personnel, making it highly practical. The sensor features an oligonucleotide probe covalently attached to magnetically separable magnetite (Fe

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