Contilisant+Tubastatin A Hybrids: Polyfunctionalized Indole Derivatives as New HDAC Inhibitor-Based Multitarget Small Molecules with In Vitro and In Vivo Activity in Neurodegenerative Diseases
2024; American Chemical Society; Linguagem: Inglês
10.1021/acs.jmedchem.4c01367
ISSN1520-4804
AutoresMireia Toledano‐Pinedo, Alicia Porro-Pérez, Linda Schäker‐Hübner, Fernando Romero, Min Dong, Abdelouahid Samadi, Pedro Almendros, Isabel Iriepa, Óscar M. Bautista‐Aguilera, M. Mercedes Rodríguez‐Fernández, Cristina Solana‐Manrique, Inmaculada Sanchis, Alba Mora-Morell, Ania Canseco Rodrìguez, Ana María Sánchez‐Pérez, Damijan Knez, Stanislav Gobec, Aina Bellver‐Sanchís, Belén Pérez, Alexey V. Dobrydnev, Aizpea Artetxe-Zurutuza, Ander Matheu, Agata Siwek, Małgorzata Wolak, Grzegorz Satała, Andrzej J. Bojarski, Agata Doroż-Płonka, Jadwiga Handzlik, Justyna Godyń, Anna Wiȩckowska, Nuria Paricio, Christian Griñán‐Ferré, Finn K. Hansen, José Marco‐Contelles,
Tópico(s)Click Chemistry and Applications
ResumoHerein, we describe the design, synthesis, and biological evaluation of 15
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