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Fatal Oropouche Virus Infections in Nonendemic Region, Brazil, 2024

2024; Centers for Disease Control and Prevention; Volume: 30; Issue: 11 Linguagem: Inglês

10.3201/eid3011.241132

1080-6059

Antônio Carlos Bandeira, Felicidade Mota Pereira, Arabela Leal, Sara P.O. Santos, Ana Cláudia Barbosa, Márcia São Pedro Leal Souza, Daniele Ribeiro de Souza, Natália Rocha Guimarães, Vagner Fonseca, Marta Giovanetti, Luíz Carlos Júnior Alcântara, André Alvarez A. Lessa, Ramon Costa Saavedra, Luiz Marcelo Ribeiro Tomé, Felipe Campos de Melo Iani, Rivia Mary Barros, Sandra Maria Oliveira da Purificação, J. Jesus, Ricardo Rosário Fonseca, Márcio Luís Valença Araújo,

Mosquito-borne diseases and control

We report acute Oropouche virus infections in 2 previously healthy women from a nonendemic region of Brazil outside the Amazon Basin. Infections rapidly progressed to hemorrhagic manifestations and fatal outcomes in 4-5 days. These cases highlight the critical need for enhanced surveillance to clarify epidemiology of this neglected disease.