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Association of beta blockers and mortality in adults with septic shock: systematic review and meta-analysis of randomized clinical trial

2024; Frontiers Media; Volume: 11; Linguagem: Inglês

10.3389/fmed.2024.1448573

2296-858X

Gustavo Adolfo Vásquez-Tirado, Claudia Vanessa Quispe-Castañeda, Edinson Dante Meregildo-Rodríguez, María del Carmen Cuadra-Campos, Niler Manuel Segura-Plasencia, Yessenia Katherin Arbayza-Ávalos, Hugo Alva-Guarniz, Wilson Marcial Guzmán-Aguilar, Petterson Zavaleta-Alaya,

Intensive Care Unit Cognitive Disorders

Septic shock still entails significant morbidity and mortality, with the heart being affected due to catecholamine overexpression and direct injury from sepsis. Therefore, the effect of β-blocking the receptors to improve performance is promising when attempting to reverse tachycardia and reduce mortality.