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Decompression Illness After Technical Diving Session in Mediterranean Sea: Oxidative Stress, Inflammation, and HBO Therapy

2024; Multidisciplinary Digital Publishing Institute; Volume: 25; Issue: 21 Linguagem: Inglês

10.3390/ijms252111367

1661-6596

Simona Mrakic‐Sposta, Andrea Brizzolari, Alessandra Vezzoli, Carmela Graci, Antonietta Cimmino, Tommaso Antonio Giacon, Cinzia Dellanoce, Alessandra Barassi, Giovanni Sesana, Gerardo Bosco,

Heme Oxygenase-1 and Carbon Monoxide

SCUBA diving poses risks due to pressure changes during descent (compression) and ascent (decompression). Decompression sickness (DCS) occurs due to gas bubble formation as the pressure decreases, causing joint pain, numbness, dizziness, or even paralysis and death. Immediate treatment involves 100% oxygen to help eliminate inert gases and hyperbaric oxygen therapy (HBOT), which is essential to reduce gas emboli formation and inflammation, thus improving symptoms. We evaluated oxy-inflammation biomarkers in the saliva and urine of nine subjects pre- and post-technical dive on the Haven wreck (GE, Italy). A case of DCS occurred during the dive. The injured diver was treated immediately with O