Optimal timing of anticoagulation after acute ischaemic stroke with atrial fibrillation (OPTIMAS): a multicentre, blinded-endpoint, phase 4, randomised controlled trial
2024; Elsevier BV; Volume: 404; Issue: 10464 Linguagem: Inglês
10.1016/s0140-6736(24)02197-4
ISSN1474-547X
AutoresDavid J. Werring, Hakim‐Moulay Dehbi, Norin Ahmed, Liz Arram, Jonathan G. Best, Maryam Balogun, Kate Bennett, Ekaterina Bordea, Emilia Caverly, Marisa Chau, David Cohen, Mairead Cullen, Caroline J Doré, Stefan T. Engelter, Robert Fenner, Gary A. Ford, Aneet Gill, Rachael Hunter, Martin James, Archana Jayanthi, Gregory Y H Lip, Sue Massingham, Macey L. Murray, Iwona Mazurczak, Philip S. Nash, Amalia Ndoutoumou, Bo Norrving, Hannah Sims, Nikola Sprigg, Thuva Vanniyasingam, Nick Freemantle,
Tópico(s)Venous Thromboembolism Diagnosis and Management
ResumoThe optimal timing of anticoagulation for patients with acute ischaemic stoke with atrial fibrillation is uncertain. We investigated the efficacy and safety of early compared with delayed initiation of direct oral anticoagulants (DOACs) in patients with acute ischaemic stroke associated with atrial fibrillation.
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