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Predictors of Hepatic Fibrosis in Type 2 Diabetes Patients with Metabolic-Dysfunction-Associated Steatotic Liver Disease

2024; Multidisciplinary Digital Publishing Institute; Volume: 12; Issue: 11 Linguagem: Inglês

10.3390/biomedicines12112542

2227-9059

Joana D’Arc Matos França de Abreu, Rossana Santiago de Sousa Azulay, Vandílson Pinheiro Rodrigues, Sterffeson Lamare Lucena de Abreu, Maria da Glória Tavares, Flávia Coelho Mohana Pinheiro, Clariano Pires de Oliveira Neto, Caio Leônidas Oliveira de Andrade, Alexandre Facundo, Adriana Guimarães Sá, Patrícia Ribeiro Azevedo, Ana Gregória Ferreira Pereira de Almeida, Durval C. Costa, Rogério Soares Castro, Marcelo Magalhães, Gilvan Cortês Nascimento, Manuel dos Santos Faria, Adalgisa de Souza Paiva Ferreira,

Alcohol Consumption and Health Effects

Approximately 25% of the world's population and more than 60% of patients with type 2 diabetes (T2D) have metabolic-dysfunction-associated steatotic liver disease (MASLD). The association between these pathologies is an important cause of morbidity and mortality in Brazil and worldwide due to the high frequency of advanced fibrosis and cirrhosis. The objective of this study was to determine the epidemiologic and clinical-laboratory profile of patients with T2D and MASLD treated at an endocrinology reference service in a state in northeastern Brazil, and to investigate the association of liver fibrosis with anthropometric and laboratory measurements.