Portal de Periódicos da CAPES

Temporal summation of pain in sickle cell disease: comparison of adolescents and young adults with chronic vs. infrequent pain

2024; Oxford University Press; Linguagem: Inglês

10.1093/jpepsy/jsae090

1465-735X

Cynthia Karlson, Harrison Dickens, Wynette Williams-Kirkwood, Maria Eugenia Bueno Tito Mascaro, Erin Jackson, Veronica Carullo, Melissa McNaull, Matthew C. Morris,

Cannabis and Cannabinoid Research

This study examined the role of central sensitization in the experience of pain among adolescents and young adults with the most severe genotypes of sickle cell disease (SCD). We hypothesized that adolescents and young adults with chronic SCD pain would demonstrate a higher perceptual response to repeated stimulation of identical intensity (i.e., temporal summation of pain, TSP) compared to counterparts with infrequent pain. We also examined psychological risk factors that can impact pain sensitivity.