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Terpyridine-based ruthenium complexes containing 4,5-diazafluoren-9-one ligand with light-driven enhancement of biological activity

2024; Royal Society of Chemistry; Linguagem: Inglês

10.1039/d4dt02562h

1477-9234

Francisca Mayara Santos de Alencar, Florêncio Sousa Gouveia Júnior, Geângela de Fátima Sousa Oliveira, Alexandre Lopes Andrade, Mayron Alves de Vasconcelos, Alejandro Pedro Ayala, Ana C. S. Gondim, Idalina M.M. de Carvalho, Carlos André Ferreira Moraes, Marcos V. Palmeira‐Mello, Alzir A. Batista, Luiz Gonzaga de França Lopes, Eduardo H. S. Sousa,

Radical Photochemical Reactions

There has been growing effort in the scientific community to develop new antibiotics to address the major threat of bacterial resistance. One promising approach is the use of metal complexes that provide broader opportunities. Among these systems, polypyridine-ruthenium(II) complexes have received particular attention as drug candidates. Here, we prepared two new ruthenium(II) complexes with the formulation [Ru(DFO)(phtpy-R)Cl](PF