Portal de Periódicos da CAPES

Persistent Short Sleep Duration From Pregnancy to 2 to 7 Years After Delivery and Metabolic Health

2024; American Medical Association; Volume: 7; Issue: 12 Linguagem: Inglês

10.1001/jamanetworkopen.2024.52204

2574-3805

Minjee Kim, Laura Elizabeth Wiener, Jace Gilbert, Rebecca B. McNeil, Kathryn J. Reid, William A. Grobman, Francesca Facco, David M. Haas, Robert M. Silver, Philip Greenland, Lynn M. Yee, Phyllis C. Zee, Wendy Dalton, Judette Louis, Brian M. Mercer, LuAnn Polito, Jay D. Iams, Cheryl Latimer, Robert C. Basner, Michelle DiVito, Karin Fuchs, Chia‐Ling Nhan‐Chang, Ameneh Onativia, Caroline Torres, Ronald J. Wapner, Matthew Hoffman, Stephanie Lynch, Maurice Davis, Uma M. Reddy, Marian Willinger, Daniel Mobley, Susan Redline, Susan Surovec, Julianne Ulanski, Shannon Barnes, Tatiana M. Foroud, Catherine L. McCormick, Emily R. Perkins, Frank P. Schubert, Alicia Winters, Aaron D. Laposky, Peggy Campbell, Alan M. Peaceman, Jessica S. Shepard, Crystal N. Williams, Barbara V. Alexander, Martha J. DeCain, Holly L. Franklin, Christopher Griggs, Tommy E. Holder, Shannon Hunter, Matthew Koch, Deborah W. McFadden, Corette B. Parker, Venkat Yetukuri, Judith H. Chung, Michael P. Nageotte, Valerie Pham, Manuel Porto, Pamela Rumney, Pathik D. Wadhwa, Deborah A. Wing, Brittany Araujo, Michal A. Elovitz, Jack Ludmir, Samuel Parry, Mary F. Peters, Grace W. Pien, M. Bickus, Steve N. Caritis, Ashi Daftary, Stephen P. Emery, Francesca Facco, Hyagriv N. Simhan, Paul Speer, George R. Saade, Kaare Christensen, M. Sean Esplin, Linda Meadows, V. Morby, J. Postma, Melanie Williams, Ashish Aneja, Kelly S. Gibson, Jessica L. Pippen, Bonnie Rosolowski, Laniece Thomas, C. Noel Bairey Merz, Natalie A. Bello, Ian Brower, Maria Marroquin, Jenna Maughan, Nathalie Sela, B. Wanke, Eun Jeong Yu, Casandra Almonte, Cande V. Ananth, Veronica Barcelona, Whitney A. Booker, Joseph Chiu, Kirsten Cleary, Natasha Ferreira Santos da Cruz, Brandy Firman, Yessenia Gutierrez, Noora Haghighi, Carla Haro, Jennifer Haythe, Tal Korem, Eliza C. Miller, Belgica Peguero, Uma M. Reddy, Jeimy Rosado Feliz, Yan Qi, C. Kitto, Jordan Nava, Amy Staples, Tetsuya Kawakita, Cathy Spong, Michael C. Honigberg, Erica-Jane Maro, Jessica Roby-Fout, Christina Scifres, Hannah Shockley, Ligia Vasquez-Hout, Haley Whipps, Brittany Yeley, Anum Minhas, Victoria L. Pemberton, Michael J. Twery, Jasmina Varagić, Kiarri N. Kershaw, Sadiya S. Khan, Elizabeth Rangel, McKenzie K. Jancsura, Courtney D. Lynch, Kartik K. Venkatesh, Jiqiang Wu, Carla Bann, Benjamin Carper, Emma G. Crenshaw, Brian Erman, Katie Fain, Carl W. Fisher, Jace Gilbert, Selen Gizlice, Sean Hanlon, M. HARRIS, Joey Hoellerich, Karen Kesler, Nick Kinsey, David LeBlond, Derek J. Marsh, T. M. McMillan, Heather Meier, Janet Moore, Eleanor Nielson, Charles E. Riggs, E. A. Rhodes, Sridevi Sattaluri, Emily W. Thomas, Vanessa Thorsten, Nathan Vandergrift, Roger R. Williams, Yii-Der Chen, Philip Huynh, Jin Kyung Kim, Nikka Shahrokni, Lizette Spiers, Amanda Thornton, Jorge A. Zavala, Abbi D. Lane‐Cordova, Caroline D. Huang, Andrea Kozai, Lisa D. Levine, Jennifer Lewey, Meaghan McCabe, Maria Monterroso, Nadia Ngom, Keri Simonette, Saisahana Subburaj, Fatoumata Sy, Lisa M. Bodnar, Samantha Bryan, Janet M. Catov, Christiana Ekekwe, Abigail Evans, Alisse Hauspurg, Lacey W. Heinsberg, Kimberly Huber, Michele D. Levine, Victoria Lopata, Christopher P. Price, Mitali Ray, Jill A. Tarr, Julia Whiteleather, Nathan R. Blue, Maggie Cook, Danielle Heil, Torri D. Metz, Josh Oliver, Dorothy Patterson, Karen C. Schliep, Lauren H. Theilen, Suzanne C. Aldous, S. Breeze, Lindsey Carlson, Sandi Dellerman, Holly Evans, Benjamin F. Hobbs, Jessica Johnson, Jake Krong, Diana Magana, Catherine Meadows, Rachel Moore, Michael Nunley, Kristin Orton, Midra Pederson, Sara St Hilaire, Kailey Tingey, N Unsworth, Bethany Barone Gibbs,

Obstructive Sleep Apnea Research

Importance Short sleep duration during pregnancy and the perimenopausal period has been associated with adverse cardiometabolic outcomes. However, it remains unclear how sleep duration changes after delivery and whether such changes are associated with the cardiometabolic health of birthing people. Objective To investigate whether persistently short sleep during pregnancy and after delivery is associated with incident hypertension and metabolic syndrome. Design, Setting, and Participants This secondary analysis of the Nulliparous Pregnancy Outcomes Study: Monitoring Mothers-to-Be Heart Health Study (NuMoM2b-HHS), an ongoing prospective cohort study, was conducted between September 5, 2023, and March 1, 2024, in 8 US academic medical centers. Participants were aged 18 years or older at NuMoM2b enrollment; recruited during their first pregnancy between October 1, 2010, and September 30, 2013; and followed up for a mean (SD) of 3.1 (0.9) years after delivery. Exposures Self-reported short sleep duration (<7 hours) during pregnancy and 2 to 7 years after delivery was defined as persistent short sleep. Main Outcomes and Measures Incident hypertension and metabolic syndrome (MetS) at follow-up. Regression models were used to estimate relative risks of incident hypertension and MetS by sleep duration pattern. Hypertension analyses excluded participants with hypertension at baseline, and MetS analyses excluded participants with MetS at baseline. Multivariable models included a priori covariates of baseline age and time from delivery to follow-up. Incident hypertension analyses included an additional covariate of body mass index at baseline. Results Among 3922 participants (mean [SD] age, 27.3 [5.4] years; 598 Hispanic [15.2%], 485 non-Hispanic Black [12.4%], and 2542 non-Hispanic White [64.8%]), 565 individuals (14.4%) experienced persistent short sleep. Non-Hispanic Black (adjusted odds ratio [aOR], 2.17; 95% CI, 1.59-2.97) and unmarried (aOR, 1.68, 95% CI, 1.29-2.19) participants were significantly more likely to experience persistent short sleep compared with non-Hispanic White and married participants, respectively. Persistent short sleep was associated with higher odds of incident MetS (aOR, 1.60; 95% CI, 1.21-2.11) but not incident hypertension (aOR, 0.91; 95% CI, 0.69-1.19). Conclusions and Relevance In this study, short sleep duration that persisted from pregnancy to 2 to 7 years after delivery was associated with a greater risk for adverse cardiometabolic outcomes. Future studies should explore whether sleep-targeted interventions during and after pregnancy are associated with improved cardiometabolic health outcomes, particularly among populations at increased risk.