Micro-TAS on Polymer Substrates Micromachined by Laser Photoablation
1998; Linguagem: Inglês
10.1007/978-94-011-5286-0_57
ISSN1556-5890
AutoresA. Schwarz, J. S. Rossier, François Bianchi, F. Reymond, Rosaria Ferrigno, Hubert H. Girault,
Tópico(s)Innovative Microfluidic and Catalytic Techniques Innovation
ResumoRecently, laser photoablation has been developed as a micromachining technique for the fabrication of micro-channel networks in polymer substrates such as polyethylene terephthalate. The channels were sealed by a lamination technique. We developed both capillary fill and electroosmotic driven devices. To illustrate the concept of single use micro-channel devices we present our current work towards a disposable ELISA (enzyme linked immunosorbent assay) for DDimer in blood plasma. The different aspects of the fabrication of the sensors (antibody immobilization, enzyme reaction and electrode fabrication) are discussed. To illustrate electroosmotic driven separations, we describe a technique that will allow efficient electrochemical detection for capillary electrophoresis and related techniques.
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