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IL-7 and TSLP receptors: twisted sisters

2014; Elsevier BV; Volume: 124; Issue: 1 Linguagem: Inglês

10.1182/blood-2014-05-574327

1528-0020

Scott K. Durum,

Autoimmune and Inflammatory Disorders Research

In this issue of Blood, Shochat et al report mutations in receptors for interleukin-7 (IL-7) and thymic stromal lymphopoietin (TSLP), resulting in a novel dimerization mechanism that drives acute lymphoblastic leukemias.