A review of 32 cases of tardive dystonia
1991; American Psychiatric Association; Volume: 148; Issue: 8 Linguagem: Inglês
10.1176/ajp.148.8.1055
ISSN1535-7228
AutoresJoanne Wojcik, W E Falk, Jasmin Fink, Jonathan Cole, A J Gelenberg,
Tópico(s)Parkinson's Disease Mechanisms and Treatments
ResumoBack to table of contents Previous article Next article No AccessA review of 32 cases of tardive dystoniaPublished Online:1 Apr 2006https://doi.org/10.1176/ajp.148.8.1055AboutSectionsView articleAbstractPDF/EPUB ToolsAdd to favoritesDownload CitationsTrack Citations ShareShare onFacebookTwitterLinked InEmail View articleAbstractOBJECTIVE: Tardive dystonia, historically combined with tardive dyskinesia, is now viewed as probably having a different pathophysiology, course, outcome, and treatment response than tardive dyskinesia. In addition, patients with tardive dystonia are reported to be younger, and most are men. This study evaluates characteristics of 32 patients with tardive dystonia and compares results to other reports. METHOD: Twenty-four patients had been referred for research purposes and were videotaped, while eight had been followed clinically. Two of the authors reviewed all available videotapes and clinical reports to assess the course of symptoms over time. For global ratings and ratings of affected body parts, two scales were used: the Abnormal Involuntary Movement Scale (AIMS) for tardive dyskinesia and a similar scale for tardive dystonia. The method of case finding does not provide incidence or prevalence data for tardive dystonia. RESULTS: Fifty-nine percent of the patients experienced onset of tardive dystonia symptoms within 6 years of antipsychotic drug exposure; women had a shorter exposure time. No patient had complete remission of tardive dystonia symptoms, and 22 were moderately or severely impaired when their movements were most prominent. CONCLUSIONS: While epidemiological studies of tardive dystonia have yet to be performed, these results support the observations of others that most patients with tardive dystonia are men, have a short history of exposure to antipsychotic drugs, and may initially present with blepharospasm. Tardive dystonia rarely remits completely, can cause notable disability, and may partially respond to anticholinergic agents. Access content To read the fulltext, please use one of the options below to sign in or purchase access. Personal login Institutional Login Sign in via OpenAthens Purchase Save for later Item saved, go to cart PPV Articles - American Journal of Psychiatry $35.00 Add to cart PPV Articles - American Journal of Psychiatry Checkout Please login/register if you wish to pair your device and check access availability. Not a subscriber? Subscribe Now / Learn More PsychiatryOnline subscription options offer access to the DSM-5 library, books, journals, CME, and patient resources. This all-in-one virtual library provides psychiatrists and mental health professionals with key resources for diagnosis, treatment, research, and professional development. Need more help? 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FiguresReferencesCited byDetailsCited byTardive syndrome: An update and mini-review from the perspective of phenomenology21 September 2020 | Journal of the Chinese Medical Association, Vol. 83, No. 12Journal of the Neurological Sciences, Vol. 389Expert Review of Neurotherapeutics, Vol. 17, No. 12Psychiatry Investigation, Vol. 14, No. 3Are Second-Generation Antipsychotics Useful in Tardive Dystonia?Clinical Neuropharmacology, Vol. 38, No. 5Tardive Dyskinesia and Tardive Dystonia With Second-Generation Antipsychotics in Non-Elderly Schizophrenic Patients Unexposed to First-Generation AntipsychoticsJournal of Clinical Psychopharmacology, Vol. 35, No. 1Neurologic Clinics, Vol. 33, No. 1Expert Opinion on Investigational Drugs, Vol. 24, No. 6The tardive syndromesRemission of Tardive Dystonia With Electroconvulsive TherapyJournal of Clinical Psychopharmacology, Vol. 29, No. 3Transient Tardive Dystonia: Overview and Case PresentationJournal of Psychiatric Practice, Vol. 14, No. 4Medication and substance-induced disorders3 January 2013Schizophrenia Research, Vol. 98, No. 1-3Expert Opinion on Pharmacotherapy, Vol. 9, No. 9The Tardive SyndromesProgress in Neuro-Psychopharmacology and Biological Psychiatry, Vol. 31, No. 5New England Journal of Medicine, Vol. 355, No. 8Remission of Tardive Dystonia (Blepharospasm) After Electroconvulsive Therapy in a Patient With Treatment-Refractory SchizophreniaThe Journal of ECT, Vol. 21, No. 2Long-term high-frequency bilateral pallidal stimulation for neuroleptic-induced tardive dystoniaJournal of Neurosurgery, Vol. 102, No. 4, Vol. 20045530CONTINUUM: Lifelong Learning in Neurology, Vol. 10Clinical Neuropharmacology, Vol. 25, No. 2Clinical Neuropharmacology, Vol. 25, No. 3CNS Drugs, Vol. 16, No. 3Psychiatry and Clinical Neurosciences, Vol. 54, No. 4Letters to the Editor1 June 1999 | The Canadian Journal of Psychiatry, Vol. 44, No. 5Biological Psychiatry, Vol. 45, No. 6Case Study: Worsening Tourette's Disorder or Withdrawal Dystonia?Journal of the American Academy of Child & Adolescent Psychiatry, Vol. 37, No. 7Movement Disorders, Vol. 13, No. 3Acta Psychiatrica Scandinavica, Vol. 98, No. 4Dysarthria: Lonely Symptom of Tardive Dystonia1 May 1997 | The Canadian Journal of Psychiatry, Vol. 42, No. 4Movement Disorders, Vol. 12, No. 4European Neuropsychopharmacology, Vol. 7, No. 4Journal of Clinical Psychopharmacology, Vol. 17, No. 6The Italian Journal of Neurological Sciences, Vol. 17, No. 6British Journal of Psychiatry, Vol. 168, No. 4International Journal of Neuroscience, Vol. 84, No. 1-4European Archives of Psychiatry and Clinical Neuroscience, Vol. 245, No. 3Movement Disorders, Vol. 9, No. 4Neurologic Concerns in Long-Term Care23 June 2016 | Journal of Pharmacy Practice, Vol. 6, No. 6, Vol. 17Dr. Wyatt and Dr. Khot ReplyRICHARD JED WYATT, and VIKRAM KHOT1 April 2006 | American Journal of Psychiatry, Vol. 149, No. 8Dr. Cole and Associates ReplyJONATHAN O. COLE, JOANNE D. WOJCIK, WILLIAM E. FALK, J. STEPHEN FINK, and ALAN J. GELENBERG1 April 2006 | American Journal of Psychiatry, Vol. 149, No. 8Antiglucocorticoid Effects of DHEA-S in Alzheimer's DiseaseFRIEDRICH LEBLHUBER, ELMAR WINDHAGER, CHRISTIAN NEUBAUER, JORG WEBER, FRANZ REISECKER, and ELIZABETH DIENSTL1 April 2006 | American Journal of Psychiatry, Vol. 149, No. 8Involuntary facial movements, not all medication-induced23 January 2015 | American Journal of Psychiatry, Vol. 149, No. 8Antiglucocorticoid effects of DHEA-S in Alzheimer's disease [published erratum appears in Am J Psychiatry 1992 Nov;149(11):1622]23 January 2015 | American Journal of Psychiatry, Vol. 149, No. 8Psychiatric Clinics of North America, Vol. 15, No. 2 Volume 148Issue 8 August 1991Pages 1055-1059 Metrics PDF download History Published online 1 April 2006 Published in print 1 August 1991
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