Defining intrinsic vs. extrinsic atopic dermatitis
2015; University of California, Davis; Volume: 21; Issue: 6 Linguagem: Inglês
10.5070/d3216027812
ISSN1087-2108
AutoresChanté Karimkhani, Jonathan I. Silverberg, Robert P. Dellavalle,
Tópico(s)Food Allergy and Anaphylaxis Research
ResumoAtopic dermatitis (AD) is a chronic, relapsing inflammatory skin condition characterized by eczematous lesions, i.e. ill-demarcated erythematous patches and plaques. AD is commonly associated with elevated immunoglobulin E (IgE) and atopic disorders, such as asthma, hay fever, and food allergies. Rackemann and Mallory were some of the first to distinguish between asthma based on the presence ("extrinsic") or absence ("intrinsic") of allergy. This distinction has subsequently been applied to AD based on the presence ("extrinsic") or absence ("intrinsic") of increased IgE and atopic disease. Although the distinction between intrinsic and extrinsic AD is widely used, it remains controversial.
Referência(s)