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The Biology of Extracellular Molecular Chaperones

2008; Wiley; Linguagem: Inglês

10.1002/9780470754030

1935-4657

Derek J. Chadwick, Jamie Goode,

Endoplasmic Reticulum Stress and Disease

Symposium on The biology of extracellular molecular chaperones, held at the Novartis Foundation, London, 5-7 June 2007 . Editors: Derek J. Chadwick (Organizer) and Jamie Goode . This symposium is based on a proposal made by Brian Henderson, R. John Ellis and A. Graham Pockley Peter Csermely Chair's introduction. Jodie Haak and Kevin C. Kregel 1962-2007: a cell stress odyssey. Discussion . Peter A. Lund and R. John Ellis The chaperone function: meanings and myths. Discussion . Peter Csermely, Tamas Korcsmaros, Istvan A. Kovacs, Mate S. Szalay and Csaba Soti Systems biology of molecular chaperone networks. Discussion . Radhey S. Gupta , Nallur B. Ramachandra, Timothy Bowes and Bhag Singh Unusual cellular disposition of the mitochondrial molecular chaperones Hsp60, Hsp70 and Hsp10. Discussion . Martha Triantafilou, Daniel Sawyer, Abdiaziz Nor, Emmanouil Vakakis and Kathy Triantafilou Cell surface molecular chaperones as endogenous modulators of the innate immune response. Discussion . A. Graham Pockley and Gabriele Multhoff Cell stress proteins in extracellular fluids: friend or foe? Discussion . Francisco J. Quintana and Irun R. Cohen HSP60 speaks to the immune system in many voices. Discussion . Stuart K. Calderwood, Jianlin Gong, Jimmy R. Theriault, Salamatu S. Mambula and Philip J. Gray Jnr Cell stress proteins: novel immunotherapeutics. Discussion . General discussion . Brian Henderson Cell stress proteins as modulators of bacteria-host interactions. Discussion . Anthony R. M. Coates, Ana Cehovin and Yanmin Hu Chaperonin 60 and macrophage activation. Discussion . Alexzander Asea Hsp70: a chaperokine. Discussion . Hajime Nakamura Extracellular functions of thioredoxin. Discussion . Carol L. Miller-Graziano, Asit De, Krzysztof Laudanski, Tara Herrmann and Sanjukta Bandyopadhyay HSP27: an anti-inflammatory and immunomodulatory stress protein acting to dampen immune function. Discussion . Gabriel S. Panayi and Valerie M. Corrigall BiP, an anti-inflammatory ER protein, is a potential new therapy for the treatment of rheumatoid arthritis. Discussion . Final discussion . Index of contributors. Subject index.