Fatigue, sleep disturbance, disability, and indices of progression of HIV infection
1992; American Psychiatric Association; Volume: 149; Issue: 4 Linguagem: Inglês
10.1176/ajp.149.4.514
ISSN1535-7228
AutoresDenis F. Darko, J. Allen McCutchan, Daniel F. Kripke, J. Christian Gillin, S. Golshan,
Tópico(s)Fibromyalgia and Chronic Fatigue Syndrome Research
ResumoBack to table of contents Previous article Next article No AccessFatigue, sleep disturbance, disability, and indices of progression of HIV infectionPublished Online:1 Apr 2006https://doi.org/10.1176/ajp.149.4.514AboutSectionsView articleAbstractPDF/EPUB ToolsAdd to favoritesDownload CitationsTrack Citations ShareShare onFacebookTwitterLinked InEmail View articleAbstractOBJECTIVE: The authors' objective was to test the hypothesis that fatigue affects the activities and employment of subjects with HIV infection and that indices of immunosuppression and inflammation may have statistical utility in predicting fatigue and sleep disturbance. METHOD: The authors prospectively asked 112 homosexual men (62 HIV- seropositive subjects and 50 HIV-seronegative comparison subjects) to complete a questionnaire on fatigue and sleep disturbance. In addition, hematocrit, WBC count, CD4+ cell number, lactate dehydrogenase, albumin, and total globulin were measured. RESULTS: For HIV- seropositive patients fatigue was significantly more of a problem and interfered more with important activities such as employment and driving than with seronegative comparison subjects. The HIV-infected patients were significantly more likely to be unemployed, to feel fatigued through more hours of the day, to sleep more, to nap more, and to have diminished midmorning alertness. The medical variables could be used to statistically predict fatigue, its interference with daily activities, and employment. CONCLUSIONS: Fatigue and sleep disturbances contribute to morbidity and disability in HIV-infected homosexual men, especially those in CDC stage IV (AIDS-related complex or AIDS). Correlation with measures of immunosuppression and inflammation and comparison between fatigued versus nonfatigued groups suggest the possibility of statistical prediction of fatigue by using these measures. Further study is needed to examine the possibility of eventual specific intervention to clinically treat HIV-related fatigue, sleepiness, and sleep disturbance. Access content To read the fulltext, please use one of the options below to sign in or purchase access. Personal login Institutional Login Sign in via OpenAthens Purchase Save for later Item saved, go to cart PPV Articles - American Journal of Psychiatry $35.00 Add to cart PPV Articles - American Journal of Psychiatry Checkout Please login/register if you wish to pair your device and check access availability. Not a subscriber? Subscribe Now / Learn More PsychiatryOnline subscription options offer access to the DSM-5 library, books, journals, CME, and patient resources. This all-in-one virtual library provides psychiatrists and mental health professionals with key resources for diagnosis, treatment, research, and professional development. Need more help? PsychiatryOnline Customer Service may be reached by emailing [email protected] or by calling 800-368-5777 (in the U.S.) or 703-907-7322 (outside the U.S.). FiguresReferencesCited byDetailsCited bySleep quality and associated factors among adult people living with HIV on follow-up at Dessie Town Governmental Health Facilities Antiretroviral Therapy Clinics, Northeast, Ethiopia, 2020, a multicenter cross-sectional study2 March 2023 | BMC Psychiatry, Vol. 23, No. 1Quality of sleep in people living with HIV in the era of highly active antiretroviral treatment21 December 2022 | International Journal of STD & AIDS, Vol. 34, No. 3Methods for home-based self-applied polysomnography: the Multicenter AIDS Cohort Study29 April 2022 | SLEEP Advances, Vol. 3, No. 1Insomnia, Health, and Health-related Quality of Life in an Urban Clinic Sample of People Living with HIV/AIDS12 August 2020 | Behavioral Sleep Medicine, Vol. 19, No. 4A New Hypothesis on Anxiety, Sleep Insufficiency, and Viral Infections; Reciprocal Links to Consider in Today's “World vs. COVID-19” Endeavors5 November 2020 | Frontiers in Psychiatry, Vol. 11Correlates of Fatigue Among South African Adolescents Living with HIV and Receiving Antiretroviral Therapy18 January 2019 | AIDS and Behavior, Vol. 23, No. 3Brain Research Bulletin, Vol. 145Frontiers in Psychiatry, Vol. 10Associations between sleep parameters, non-communicable diseases, HIV status and medications in older, rural South Africans23 November 2018 | Scientific Reports, Vol. 8, No. 1Journal of the International Neuropsychological Society, Vol. 24, No. 10Psychology & Health, Vol. 33, No. 3Frontiers in Psychiatry, Vol. 9Diagnostics, Vol. 8, No. 3Burden of sleep disturbances and associated risk factors: A cross-sectional survey among HIV-infected persons on antiretroviral therapy across China16 June 2017 | Scientific Reports, Vol. 7, No. 1Sleep Health, Vol. 2, No. 4Neuro-OncologyHypersomnias Other Than Narcolepsy: Differential DiagnosisDepressive symptoms and fatigue as mediators of relationship between poor sleep factors and medication adherence in HIV-positive women8 September 2015 | Journal of Research in Nursing, Vol. 20, No. 6Sleep Medicine, Vol. 16, No. 8Journal of Immunology Research, Vol. 2015Sleep and HIV Disease14 August 2015Mood Disorders, Delirium, and Other Neurobehavioral Symptoms and Disorders in the HAART Era9 April 2014Sleep quality in efavirenz-treated Chinese HIV patients – comparing between GT and GG genotype of CYP2B6-516 G/T polymorphisms23 July 2013 | International Journal of STD & AIDS, Vol. 25, No. 3PLoS ONE, Vol. 9, No. 7African Journal of AIDS Research, Vol. 13, No. 1Lack of Energy: An Important and Distinct Component of HIV-Related Fatigue and Daytime FunctionJournal of Pain and Symptom Management, Vol. 45, No. 2Journal of the Association of Nurses in AIDS Care, Vol. 24, No. 1Psychoneuroendocrinology, Vol. 38, No. 11HIV Medicine, Vol. 14, No. 4Biological Research For Nursing, Vol. 15, No. 2Journal of Psychosomatic Research, Vol. 72, No. 6Sleep Medicine Clinics, Vol. 7, No. 2Neurologic Clinics, Vol. 30, No. 4Clinical Infectious Diseases, Vol. 54, No. 10Brain tumors, infections, and other CNS causes of sleepinessQuality of Life Research, Vol. 20, No. 9Journal of NeuroVirology, Vol. 17, No. 1AIDS Patient Care and STDs, Vol. 25, No. 9Journal of Clinical Nursing, Vol. 20, No. 15-16AIDS and Behavior, Vol. 14, No. 6Psychosomatics, Vol. 50, No. 5Journal of the Association of Nurses in AIDS Care, Vol. 20, No. 1Chest, Vol. 135, No. 2Sleep Disturbances in Women With HIV or AIDSNursing Research, Vol. 57, No. 5Physiological Correlates of HIV-Related Fatigue1 February 2008 | Clinical Nursing Research, Vol. 17, No. 1AIDS Care, Vol. 20, No. 7Sleep Medicine Clinics, Vol. 2, No. 1Physical Therapy Reviews, Vol. 12, No. 1Journal of the Association of Nurses in AIDS Care, Vol. 17, No. 1Rehabilitation Psychology, Vol. 51, No. 2Issues in Mental Health Nursing, Vol. 27, No. 2Journal of Advanced Nursing, Vol. 55, No. 2Journal of Clinical Nursing, Vol. 15, No. 9Insomnia in HIV Infection: A Systematic Review of Prevalence, Correlates, and ManagementPsychosomatic Medicine, Vol. 67, No. 2Quality of Life Research, Vol. 14, No. 4Clinical Psychology Review, Vol. 25, No. 5The Clinical Journal of Pain, Vol. 21, No. 3Journal of Advanced Nursing, Vol. 52, No. 4HIV Medicine, Vol. 6, No. 5American Journal of Physiology-Regulatory, Integrative and Comparative Physiology, Vol. 289, No. 3Aerobic Exercise Dysfunction in Human Immunodeficiency Virus: A Potential Link to Physical DisabilityPhysical Therapy, Vol. 84, No. 7Physiological and Psychological Correlates of Fatigue in HIV Disease25 July 2016 | Biological Research For Nursing, Vol. 6, No. 1Physiological and Psychological Correlates of Sleep in HIV Infection25 July 2016 | Clinical Nursing Research, Vol. 13, No. 1Médecine du Sommeil, Vol. 1, No. 2Journal of Psychosomatic Research, Vol. 57, No. 5Medical Clinics of North America, Vol. 88, No. 3Clinical Infectious Diseases, Vol. 38, No. 10, Vol. 20042337Comparative Study of Anxiety, Depression, Somatization, Functional Disability, and Illness Attribution in Adolescents With Chronic Fatigue or Migraine1 April 2003 | Pediatrics, Vol. 111, No. 4Physiological and Psychological Markers Associated with HIV-Related Fatigue25 July 2016 | Clinical Nursing Research, Vol. 12, No. 1Archives of Physical Medicine and Rehabilitation, Vol. 84, No. 11Holistic Nursing Practice, Vol. 17, No. 2Holistic Nursing Practice, Vol. 17, No. 2Comorbidity of depression with other medical diseases in the elderlyBiological Psychiatry, Vol. 52, No. 6Journal of the Association of Nurses in AIDS Care, Vol. 13, No. 1The Journal of Infectious Diseases, Vol. 185, No. s2Psychosomatics, Vol. 43, No. 4Journal of Neuroimmunology, Vol. 119, No. 2Journal of the Association of Nurses in AIDS Care, Vol. 12, No. 3Journal of the Association of Nurses in AIDS Care, Vol. 12Journal of the Association of Nurses in AIDS Care, Vol. 12, No. 1Journal of the Association of Nurses in AIDS Care, Vol. 12, No. 6Neurobiology of Disease, Vol. 7, No. 4Biological Psychiatry, Vol. 47, No. 7International Journal of Nursing Studies, Vol. 37, No. 5Journal of Advanced Nursing, Vol. 32, No. 5Archives of Physical Medicine and Rehabilitation, Vol. 81, No. 11Sleep Disturbances in Children With Human Immunodeficiency Virus Infection1 November 1999 | Pediatrics, Vol. 104, No. 5International Journal of Nursing Studies, Vol. 36, No. 4Journal of Neuroimmunology, Vol. 97, No. 1-2Journal of the Association of Nurses in AIDS Care, Vol. 10, No. 3Journal of the Association of Nurses in AIDS Care, Vol. 10, No. 5Journal of the Association of Nurses in AIDS Care, Vol. 10, No. 5Sleep Medicine Reviews, Vol. 3, No. 4Journal of Obstetric, Gynecologic & Neonatal Nursing, Vol. 28, No. 1Journal of Obstetric, Gynecologic & Neonatal Nursing, Vol. 28, No. 2Women with HIV: Living with Symptoms1 July 2016 | Western Journal of Nursing Research, Vol. 20, No. 4Testosterone as a treatment for fatigue in HIV+ menGeneral Hospital Psychiatry, Vol. 20, No. 4Fatigue in Ambulatory AIDS PatientsJournal of Pain and Symptom Management, Vol. 15, No. 3Disease severity, physical limitations and depression in hiv-infected menJournal of Psychosomatic Research, Vol. 44, No. 2Journal of Advanced Nursing, Vol. 28, No. 2Hodgkin’s disease: Quality of life in future trialsAnnals of Oncology, Vol. 9Psychosomatic Medicine, Vol. 60, No. 6Journal of Acquired Immune Deficiency Syndromes and Human Retrovirology, Vol. 19, No. 3Fatigue, Depression, and Quality of Life in HIV-Positive Men1 September 1997 | Journal of Psychosocial Nursing and Mental Health Services, Vol. 35, No. 9Journal of Musculoskeletal Pain, Vol. 5, No. 4Viabilidad de la farmacoterapia en trastornos del espectro afectivo relacionados con el VIH: un ensayo abierto con fluvoxamina12 May 2020 | European psychiatry (Ed. Española), Vol. 3, No. 3DEPRESSION AND HIVNursing Clinics of North America, Vol. 31, No. 1Annals of Behavioral Medicine, Vol. 18, No. 1Feasibility of pharmacotherapy in HIV-related affective spectrum disorders: an open trial with fluvoxamineEuropean Psychiatry, Vol. 11, No. 1Journal of the Association of Nurses in AIDS Care, Vol. 7, No. 1Journal of the Association of Nurses in AIDS Care, Vol. 7, No. 3International Journal of Nursing Terminologies and Classifications, Vol. 7, No. 2Disability and Rehabilitation, Vol. 18, No. 5Somatic symptoms and HIV infection: relationship to depressive symptoms and indicators of HIV disease1 April 2006 | American Journal of Psychiatry, Vol. 152, No. 12Annals of Behavioral Medicine, Vol. 17, No. 4Journal of Psychosomatic Research, Vol. 39, No. 3Advances in Neuroimmunology, Vol. 5, No. 1Advances in Neuroimmunology, Vol. 5, No. 1Journal of Pharmaceutical Care in Pain & Symptom Control, Vol. 3, No. 3-4Clinical Psychology & Psychotherapy, Vol. 1, No. 2 Volume 149Issue 4 April 1992Pages 514-520 Metrics PDF download History Published online 1 April 2006 Published in print 1 April 1992
Referência(s)