Portal de Periódicos da CAPES

Nuclear Receptors

2003; Cell Press; Volume: 114; Issue: 3 Linguagem: Inglês

10.1016/s0092-8674(03)00599-3

1097-4172

Borja Belandia, Malcolm G. Parker,

Chromatin Remodeling and Cancer

Nuclear receptors (NRs) are a large family of ligand-induced transcription factors that include the vitamin D receptor. The recent discovery of WINAC, a novel ATP-dependent chromatin remodeling complex, has shed new light on the molecular mechanisms by which the vitamin D receptor controls gene expression with unexpected clinical implications.