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THz Exposure of Whole Blood for the Study of Biological Effects on Human Lymphocytes.

2003; Springer Science+Business Media; Volume: 29; Issue: 2/3 Linguagem: Inglês

10.1023/a

1573-0689

Maria Rosaria Scarfı̀, Miriam Romano, Roberta Di Pietro, Olga Zeni, Andréa S. Doria, Gian Piero Gallerano, E. Giovenale, Gabriele Messina, Antonella Lai, G. Campurra, D. Coniglio, Marco D’Arienzo,

Radiation Effects and Dosimetry

The aim of the present study is toinvestigate the genotoxic effect of THzradiation in human peripheral bloodlymphocytes following 20 minutes exposureto 1 mW average power Free Electron Laserradiation in the frequency range 120-140GHz. For this purpose 9 healthy donors wereemployed and cytokinesis block techniquewas applied to study micronucleusfrequency and cell proliferation. Theresults obtained indicate that all theelectromagnetic conditions adopted so far do not alter the investigated parameters,suggesting absence of direct chromosomaldamage and alteration of cell cyclekinetics (two tailed paired Student's test:p> 0.05 in all cases).