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EEG Coherence as Measure of Depressive Disorder

2009; Springer Nature; Linguagem: Inglês

10.1007/978-3-540-89208-3_83

1727-1983

Anna Suhhova, Maie Bachmann, Kaire Aadamsoo, Ülle Võhma, Jaanus Lass, Hiie Hinrikus,

Neural dynamics and brain function

The aim of this study was to investigate the changes in the EEG coherence produced by major depressive disorder. The experiments were carried out on two groups of volunteers: a group of healthy subjects and a group of patients with major depressive disorder. Each group consisted of 18 female subjects. During 30 min experiment resting EEG was recorded. The coherence values were calculated for FP1-T3 - FP2-T4, T3-P3 - T4-P4 and P3-O1 - P4-O2 channel pairs. The EEG theta (4–8 Hz), alpha (8–13 Hz), beta1 (13–20 Hz) and beta2 (20–40 Hz) frequency bands were selected for analysis. The experiments demonstrated no significant changes in the EEG coherence between healthy subjects and patients with depression. The depressed patients showed reduced coherence values compared to healthy control in alpha rhythm in temporal-parietal and parietal-occipital brain regions, in beta2 rhythm in temporal-parietal brain region and in theta rhythm in frontal-temporal brain region. Results of this study reveal coherence to be unstable indicator of depression.