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(±)-huprine Y, (-)-huperzine A and tacrine do not show neuroprotective properties in an apoptotic model of neuronal cytoskeletal alteration

2005; IOS Press; Volume: 6; Issue: 6 Linguagem: Inglês

10.3233/jad-2004-6601

1875-8908

Elvira G. Jordà, Ester Verdaguer, A. Jiménez, A.M. Canudas, Víctor Rimbau, Pelayo Camps, Diego Muñoz‐Torrero, Antoni Camins, Mercè Pallàs,

Alzheimer's disease research and treatments

Acetylcholinesterase inhibitors (AChEI) are among the drugs most widely used in the treatment of Alzheimer's disease. They increase the levels of acetylcholine and thus improve the cognitive symptoms that are impaired. We tested whether specific AChE