Hypermineralocorticoidism : The Sole Clinical Manifestation Of An Adrenal Cortical Carcinoma
1972; Taylor & Francis; Volume: 27; Issue: 1-2 Linguagem: Inglês
10.1080/17843286.1972.11716810
ISSN2295-3337
AutoresR. Six, R Leclercq, F. Noeninckx,
Tópico(s)Pituitary Gland Disorders and Treatments
ResumoSummaryAn adrenocortical carcinoma in a 54 year old female patient is reported. Arterial hypertension, muscular weakness, hypokalemic alkalosis and urinary potassium loss were the prominent features. Although plasma corticol was increased, there were no clinical signs of hypercortisolism. Surgical removal of the tumor appeared to be impossible; o p ’ DDD therapy achieved to normalize temporarily the urinary excretion not only of 17 hydroxycorticoids and of 17 ketosteroids but also of tetrahydroaldosterone.The pathogenesis of the mineralocorticoid syndrome and the influence of o p ’ DDD on the adrenocortical aldosterone production are discussed.
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