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Pancreatic exocrine insufficiency in pancreatic cancer: A review of the literature

2015; Elsevier BV; Volume: 47; Issue: 12 Linguagem: Inglês

10.1016/j.dld.2015.06.015

1878-3562

Michael J. Bartel, H. Asbun, John Stauffer, Massimo Raimondo,

Pancreatic function and diabetes

Abstract Pancreatic exocrine insufficiency is a well-documented complication of chronic pancreatitis; however, study results of pancreatic exocrine insufficiency in pancreatic cancer are less consistent. This applies for patients who are treated non-surgically and those who undergo curative pancreatic cancer resection. This review article summarizes relevant studies addressing pancreatic exocrine insufficiency in pancreatic cancer, with particular differentiation between non-surgically and surgically treated patients, as well as between the different surgeries. We also summarize studies addressing pancreatic enzyme replacement therapy in pancreatic cancer.