Portal de Periódicos da CAPES

Hepatic artery ligation and tumor necrosis in the liver.

1966; National Institutes of Health; Volume: 59; Issue: 3 Linguagem: Inglês

Wataru Mori, Masaki MASUDA, Tadahiko MIYANAGA,

Cancer Diagnosis and Treatment

A ccidental ligation of the hepatic artfT> an undesirable but fortunately infreqrrent event during surgery, has often been discussed from various viewpoints. However, as far as we know, little has been written about the consequences of this occurrence in relation to neoplasm in the human liver. It has long been postulated that tumor tissue in the liver is nourished almost exclusively by arterial blood, while the normal liver tissue receives blood from both arterial and portal systems. Thus, a comparison of the fates of liver tumor and surrounding normal liver tissue, following hepatic artery ligation, would seem to interest both pathologists and clinical doctors. Moreover, in relation to the recent method of cancer chemotherapy by arterial infusion, it is important to know the specific source of blood supply to the hepatic tumor tissue. In the Department of Pathology at the Tokyo Medical and Dental College, a recent autopsy demonstrated unique findings concerning the above problem. The purpose of this report is to describe the case and, through it, draw conclusions as to the special character of the blood supply to metastatic tumor tissue in the liver.