Portal de Periódicos da CAPES

Prediction of outcome in mania by mood-congruent or mood-incongruent psychotic features

1992; American Psychiatric Association; Volume: 149; Issue: 11 Linguagem: Inglês

10.1176/ajp.149.11.1580

1535-7228

Mauricio Tohen, Ming T. Tsuang, Daniel C. Goodwin,

Psychosomatic Disorders and Their Treatments

The aim of this study was to determine the significance of mood congruence of psychotic features in mania as a predictor of outcome.Fifty-four patients with bipolar disorder were followed prospectively for 4 years after recovery from an episode of mania with psychotic features. Assessments of residential and occupational status, interepisode symptoms, and episode recurrences were made at 6 and 48 months after recovery. Categorical outcomes were evaluated by logistic regression and recurrence risk with survival analysis.Mood-incongruent psychotic features during the index manic episode predicted a shorter time in remission at 4 years (hazard ratio = 2.6), and Schneiderian first-rank symptoms predicted poor residential status at 4 years (odds ratio = 20.1).Differentiation of mood congruence of psychotic features in mania evidently has prognostic validity and, therefore, has utility as a nosological characteristic.