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BIBTEX RIS

Short-term mortality and prognostic factors related to status epilepticus

2015; Thieme Medical Publishers (Germany); Volume: 73; Issue: 8 Linguagem: Inglês

10.1590/0004-282x20150082

ISSN

1678-4227

Autores

Fernando Gustavo Stelzer, Guilherme de Oliveira Bustamante, Heidi H. Sander, Américo Ceiki Sakamoto, Regina Maria França Fernandes,

Tópico(s)

Neuroscience and Neuropharmacology Research

Resumo

Status epilepticus (SE) is associated with significant morbidity and mortality, and there is some controversy concerning predictive indicators of outcome. Our main goal was to determine mortality and to identify factors associated with SE prognosis.This prospective study in a tertiary-care university hospital, included 105 patients with epileptic seizures lasting more than 30 minutes. Mortality was defined as death during hospital admission.The case-fatality rate was 36.2%, which was higher than in previous studies. In univariate analysis, mortality was associated with age, previous epilepsy, complex focal seizures; etiology, recurrence, and refractoriness of SE; clinical complications, and focal SE. In multivariate analysis, mortality was associated only with presence of clinical complications.Mortality associated with SE was higher than reported in previous studies, and was not related to age, specific etiology, or SE duration. In multivariate analysis, mortality was independently related to occurrence of medical complications.

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