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5-Hydroxytryptamine-3 Antagonists: A New Class of Potent Antiemetics in Cancer Therapy

1991; Springer Science+Business Media; Linguagem: Inglês

10.1007/978-3-642-84138-5_10

2197-6767

M. Soukop,

Pharmacological Effects and Toxicity Studies

For many years nausea and vomiting have been recognized as side-effects of numerous chemotherapeutic regimens. The development of the useful new agent cisplatin, due with its powerful emetic effect, highlighted this patient problem.