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Genetic risk factors of chronic obstructive pulmonary disease

2002; EMH Swiss Medical Publishers Ltd.; Linguagem: Inglês

10.4414/smw.2002.09752

0036-7672

Ladina Joos, Peter D. Paré, Andrew J. Sandford,

Neuroscience of respiration and sleep

Cigarette smoking is the major risk factor for chronic obstructive pulmonary disease (COPD). However, only a minority of cigarette smokers develop symptomatic disease. Family and twin studies suggest that genetic factors also contribute to the development of COPD. We present a detailed literature review of the genes which have been investigated as potential risk factors for this disease.