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Avaliação da Doença de Alzheimer pela Análise Multiespectral de Imagens DW-MR por Mapas Auto-Organizados de Kohonen como Alternativa aos Mapas ADC

2007; Springer Nature; Linguagem: Inglês

10.1007/978-3-540-74471-9_92

1727-1983

Wellington Pinheiro dos Santos, Ricardo E. de Souza, A. F. D. e Silva, P.B. Santos Filho,

Optical Imaging and Spectroscopy Techniques

Alzheimer's disease is the most common cause of dementia, yet hard to diagnose precisely without invasive techniques, particularly at the onset of the disease. This work approaches image analysis and classification of synthetic multispectral images composed by diffusion-weighted magnetic resonance (DW-MR) cerebral images for the evaluation of cerebrospinal fluid area and its correlation with the advance of Alzheimer's disease. The MR images were acquired from an image system by a clinical 1.5 T tomographer. The classification methods are based on multilayer perceptrons and Kohonen self-organized maps. The classification results are used as an alternative to the usual analysis of the ADC map.